Log in to save to my catalogue

Rpn1 provides adjacent receptor sites for substrate binding and deubiquitination by the proteasome

Rpn1 provides adjacent receptor sites for substrate binding and deubiquitination by the proteasome

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4980823

Rpn1 provides adjacent receptor sites for substrate binding and deubiquitination by the proteasome

About this item

Full title

Rpn1 provides adjacent receptor sites for substrate binding and deubiquitination by the proteasome

Publisher

United States: American Association for the Advancement of Science

Journal title

Science (American Association for the Advancement of Science), 2016-02, Vol.351 (6275), p.831-831

Language

English

Formats

Publication information

Publisher

United States: American Association for the Advancement of Science

More information

Scope and Contents

Contents

Hundreds of pathways for degradation converge at ubiquitin recognition by a proteasome. Here, we found that the five known proteasomal ubiquitin receptors in yeast are collectively nonessential for ubiquitin recognition and identified a sixth receptor, Rpn1. A site ( T1: ) in the Rpn1 toroid recognized ubiquitin and ubiquitin-like ( UBL: ) domains...

Alternative Titles

Full title

Rpn1 provides adjacent receptor sites for substrate binding and deubiquitination by the proteasome

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4980823

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4980823

Other Identifiers

ISSN

0036-8075

E-ISSN

1095-9203

DOI

10.1126/science.aad9421

How to access this item