Editing Transgenic DNA Components by Inducible Gene Replacement in Drosophila melanogaster
Editing Transgenic DNA Components by Inducible Gene Replacement in Drosophila melanogaster
About this item
Full title
Author / Creator
Publisher
United States: Genetics Society of America
Journal title
Language
English
Formats
Publication information
Publisher
United States: Genetics Society of America
Subjects
More information
Scope and Contents
Contents
Gene conversions occur when genomic double-strand DNA breaks (DSBs) trigger unidirectional transfer of genetic material from a homologous template sequence. Exogenous or mutated sequence can be introduced through this homology-directed repair (HDR). We leveraged gene conversion to develop a method for genomic editing of existing transgenic insertio...
Alternative Titles
Full title
Editing Transgenic DNA Components by Inducible Gene Replacement in Drosophila melanogaster
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4981265
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4981265
Other Identifiers
ISSN
1943-2631,0016-6731
E-ISSN
1943-2631
DOI
10.1534/genetics.116.191783
