Short-term intratracheal use of PEG-modified IL-2 and glucocorticoid persistently alleviates asthma...
Short-term intratracheal use of PEG-modified IL-2 and glucocorticoid persistently alleviates asthma in a mouse model
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Author / Creator
Wu, Kefei , Ma, Jiexian , Bai, Weiya , Cui, Xiaoxian , Han, Tao , Wang, Shiyuan , Xie, Youhua and Xie, Yanhui
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Regulatory T (Treg) cells play an important role in allergic airway diseases and upregulation of Treg cells is a potential therapeutic strategy for asthma. In this study, we show that short-term intratracheal use of IL-2 combined with glucocorticoid alleviates antigen-induced airway inflammation and reduces airway hyperresponsiveness by expanding a...
Alternative Titles
Full title
Short-term intratracheal use of PEG-modified IL-2 and glucocorticoid persistently alleviates asthma in a mouse model
Authors, Artists and Contributors
Author / Creator
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4985708
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4985708
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep31562
