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Tamoxifen Resistance: Emerging Molecular Targets

Tamoxifen Resistance: Emerging Molecular Targets

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5000752

Tamoxifen Resistance: Emerging Molecular Targets

About this item

Full title

Tamoxifen Resistance: Emerging Molecular Targets

Publisher

Switzerland: MDPI AG

Journal title

International journal of molecular sciences, 2016-08, Vol.17 (8), p.1357-1357

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

17β-Estradiol (E2) plays a pivotal role in the development and progression of breast cancer. As a result, blockade of the E2 signal through either tamoxifen (TAM) or aromatase inhibitors is an important therapeutic strategy to treat or prevent estrogen receptor (ER) positive breast cancer. However, resistance to TAM is the major obstacle in endocri...

Alternative Titles

Full title

Tamoxifen Resistance: Emerging Molecular Targets

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5000752

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5000752

Other Identifiers

ISSN

1422-0067,1661-6596

E-ISSN

1422-0067

DOI

10.3390/ijms17081357

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