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EGFR regulates macrophage activation and function in bacterial infection

EGFR regulates macrophage activation and function in bacterial infection

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5004944

EGFR regulates macrophage activation and function in bacterial infection

About this item

Full title

EGFR regulates macrophage activation and function in bacterial infection

Publisher

United States: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2016-09, Vol.126 (9), p.3296-3312

Language

English

Formats

Publication information

Publisher

United States: American Society for Clinical Investigation

More information

Scope and Contents

Contents

EGFR signaling regulates macrophage function, but its role in bacterial infection has not been investigated. Here, we assessed the role of macrophage EGFR signaling during infection with Helicobacter pylori, a bacterial pathogen that causes persistent inflammation and gastric cancer. EGFR was phosphorylated in murine and human macrophages during H....

Alternative Titles

Full title

EGFR regulates macrophage activation and function in bacterial infection

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5004944

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5004944

Other Identifiers

ISSN

0021-9738

E-ISSN

1558-8238

DOI

10.1172/JCI83585

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