Variation in the glucose transporter gene SLC2A2 is associated with glycemic response to metformin
Variation in the glucose transporter gene SLC2A2 is associated with glycemic response to metformin
About this item
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Author / Creator
Zhou, Kaixin , Yee, Sook Wah , Seiser, Eric L , van Leeuwen, Nienke , Tavendale, Roger , Bennett, Amanda J , Groves, Christopher J , Coleman, Ruth L , van der Heijden, Amber A , Beulens, Joline W , de Keyser, Catherine E , Zaharenko, Linda , Rotroff, Daniel M , Out, Mattijs , Jablonski, Kathleen A , Chen, Ling , Javorský, Martin , Židzik, Jozef , Levin, Albert M , Williams, L Keoki , Dujic, Tanja , Semiz, Sabina , Kubo, Michiaki , Chien, Huan-Chieh , Maeda, Shiro , Witte, John S , Wu, Longyang , Tkáč, Ivan , Kooy, Adriaan , van Schaik, Ron H N , Stehouwer, Coen D A , Logie, Lisa , Sutherland, Calum , Klovins, Janis , Pirags, Valdis , Hofman, Albert , Stricker, Bruno H , Motsinger-Reif, Alison A , Wagner, Michael J , Innocenti, Federico , Hart, Leen M 't , Holman, Rury R , McCarthy, Mark I , Hedderson, Monique M , Palmer, Colin N A , Florez, Jose C , Giacomini, Kathleen M , Pearson, Ewan R , DPP Investigators , MetGen Investigators and ACCORD Investigators
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Ewan Pearson, Kathleen Giacomini and the Metformin Genetics Consortium perform a genome-wide association study for glycemic response to the antidiabetic drug metformin. They find an intronic allele of the GLUT2 glucose transporter gene that associates with greater metformin action, an effect that is more pronounced in obese individuals.
Metformi...
Alternative Titles
Full title
Variation in the glucose transporter gene SLC2A2 is associated with glycemic response to metformin
Authors, Artists and Contributors
Author / Creator
Yee, Sook Wah
Seiser, Eric L
van Leeuwen, Nienke
Tavendale, Roger
Bennett, Amanda J
Groves, Christopher J
Coleman, Ruth L
van der Heijden, Amber A
Beulens, Joline W
de Keyser, Catherine E
Zaharenko, Linda
Rotroff, Daniel M
Out, Mattijs
Jablonski, Kathleen A
Chen, Ling
Javorský, Martin
Židzik, Jozef
Levin, Albert M
Williams, L Keoki
Dujic, Tanja
Semiz, Sabina
Kubo, Michiaki
Chien, Huan-Chieh
Maeda, Shiro
Witte, John S
Wu, Longyang
Tkáč, Ivan
Kooy, Adriaan
van Schaik, Ron H N
Stehouwer, Coen D A
Logie, Lisa
Sutherland, Calum
Klovins, Janis
Pirags, Valdis
Hofman, Albert
Stricker, Bruno H
Motsinger-Reif, Alison A
Wagner, Michael J
Innocenti, Federico
Hart, Leen M 't
Holman, Rury R
McCarthy, Mark I
Hedderson, Monique M
Palmer, Colin N A
Florez, Jose C
Giacomini, Kathleen M
Pearson, Ewan R
DPP Investigators
MetGen Investigators
ACCORD Investigators
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5007158
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5007158
Other Identifiers
ISSN
1061-4036
E-ISSN
1546-1718
DOI
10.1038/ng.3632
