Pathogenesis of FUS-associated ALS and FTD: insights from rodent models
Pathogenesis of FUS-associated ALS and FTD: insights from rodent models
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Publisher
England: BioMed Central Ltd
Journal title
Language
English
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Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
Disruptions to genes linked to RNA processing and homeostasis are implicated in the pathogenesis of two pathologically related but clinically heterogeneous neurodegenerative diseases, amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Mutations in the Fused-in-Sarcoma (FUS) gene encoding a 526 amino-acid RNA-binding protein are...
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Full title
Pathogenesis of FUS-associated ALS and FTD: insights from rodent models
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5011941
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5011941
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ISSN
2051-5960
E-ISSN
2051-5960
DOI
10.1186/s40478-016-0358-8
