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Pathogenesis of FUS-associated ALS and FTD: insights from rodent models

Pathogenesis of FUS-associated ALS and FTD: insights from rodent models

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5011941

Pathogenesis of FUS-associated ALS and FTD: insights from rodent models

About this item

Full title

Pathogenesis of FUS-associated ALS and FTD: insights from rodent models

Publisher

England: BioMed Central Ltd

Journal title

Acta neuropathologica communications, 2016-09, Vol.4 (1), p.99-99, Article 99

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Disruptions to genes linked to RNA processing and homeostasis are implicated in the pathogenesis of two pathologically related but clinically heterogeneous neurodegenerative diseases, amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Mutations in the Fused-in-Sarcoma (FUS) gene encoding a 526 amino-acid RNA-binding protein are...

Alternative Titles

Full title

Pathogenesis of FUS-associated ALS and FTD: insights from rodent models

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5011941

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5011941

Other Identifiers

ISSN

2051-5960

E-ISSN

2051-5960

DOI

10.1186/s40478-016-0358-8

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