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Binding affinity of amyloid oligomers to cellular membranes is a generic indicator of cellular dysfu...

Binding affinity of amyloid oligomers to cellular membranes is a generic indicator of cellular dysfu...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5020652

Binding affinity of amyloid oligomers to cellular membranes is a generic indicator of cellular dysfunction in protein misfolding diseases

About this item

Full title

Binding affinity of amyloid oligomers to cellular membranes is a generic indicator of cellular dysfunction in protein misfolding diseases

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2016-09, Vol.6 (1), p.32721-32721, Article 32721

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The conversion of peptides or proteins from their soluble native states into intractable amyloid deposits is associated with a wide range of human disorders. Misfolded protein oligomers formed during the process of aggregation have been identified as the primary pathogenic agents in many such conditions. Here, we show the existence of a quantitativ...

Alternative Titles

Full title

Binding affinity of amyloid oligomers to cellular membranes is a generic indicator of cellular dysfunction in protein misfolding diseases

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5020652

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5020652

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/srep32721

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