Oncogenically active MYD88 mutations in human lymphoma
Oncogenically active MYD88 mutations in human lymphoma
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Author / Creator
Ngo, Vu N. , Young, Ryan M. , Schmitz, Roland , Jhavar, Sameer , Xiao, Wenming , Lim, Kian-Huat , Kohlhammer, Holger , Xu, Weihong , Yang, Yandan , Zhao, Hong , Shaffer, Arthur L. , Romesser, Paul , Wright, George , Powell, John , Rosenwald, Andreas , Muller-Hermelink, Hans Konrad , Ott, German , Gascoyne, Randy D. , Connors, Joseph M. , Rimsza, Lisa M. , Campo, Elias , Jaffe, Elaine S. , Delabie, Jan , Smeland, Erlend B. , Fisher, Richard I. , Braziel, Rita M. , Tubbs, Raymond R. , Cook, J. R. , Weisenburger, Denny D. , Chan, Wing C. and Staudt, Louis M.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
MYD88 signalling in cancer
RNA interference screening and high-throughput RNA resequencing have been used to reveal oncogenic mutations in the signalling adapter MYD88 in human lymphomas. One amino acid substitution, L265P, was found in 29% of biopsies from patients with the activated B-cell-like subtype of diffuse large B-cell lymphoma. The sam...
Alternative Titles
Full title
Oncogenically active MYD88 mutations in human lymphoma
Authors, Artists and Contributors
Author / Creator
Young, Ryan M.
Schmitz, Roland
Jhavar, Sameer
Xiao, Wenming
Lim, Kian-Huat
Kohlhammer, Holger
Xu, Weihong
Yang, Yandan
Zhao, Hong
Shaffer, Arthur L.
Romesser, Paul
Wright, George
Powell, John
Rosenwald, Andreas
Muller-Hermelink, Hans Konrad
Ott, German
Gascoyne, Randy D.
Connors, Joseph M.
Rimsza, Lisa M.
Campo, Elias
Jaffe, Elaine S.
Delabie, Jan
Smeland, Erlend B.
Fisher, Richard I.
Braziel, Rita M.
Tubbs, Raymond R.
Cook, J. R.
Weisenburger, Denny D.
Chan, Wing C.
Staudt, Louis M.
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5024568
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5024568
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature09671
