Mitotic MELK-eIF4B signaling controls protein synthesis and tumor cell survival
Mitotic MELK-eIF4B signaling controls protein synthesis and tumor cell survival
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
The protein kinase maternal and embryonic leucine zipper kinase (MELK) is critical for mitotic progression of cancer cells; however, its mechanisms of action remain largely unknown. By combined approaches of immunoprecipitation/mass spectrometry and peptide library profiling, we identified the eukaryotic translation initiation factor 4B (eIF4B) as...
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Full title
Mitotic MELK-eIF4B signaling controls protein synthesis and tumor cell survival
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5024598
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5024598
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1606862113
