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ArticlesPeer ReviewedFull Text
Cancer metabolism: fatty acid oxidation in the limelight
Author / Creator:Carracedo, Arkaitz ; Cantley, Lewis C. ; Pandolfi, Pier Paolo
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Cancer, 2013-04, Vol.13 (4), p.227-232
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Newsletter articlesFull Text
INTERNATIONAL PATENT: CORNELL UNIVERSITY, THE BRIGHAM AND WOMEN'S HOSPITAL, INC., CANTLEY, LEWIS C., KUCHROO, VIJAY KUMAR, SCHRAMM, MARKUS ALEXANDER, DIXON, KAREN OLIVIA FILES APPLICATION FOR "LOSS OF...
Publisher:Washington, D.C: HT Digital Streams Limited
Journal title:US Fed News Service, Including US State News, 2022
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Newsletter articlesFull Text
INTERNATIONAL PATENT: GONCALVES, MARCUS , CANTLEY, LEWIS C. , YUN, JIHYE FILES APPLICATION FOR "ANTI-FRUCTOSE THERAPY FOR COLORECTAL AND SMALL INTESTINE CANCERS"
Publisher:Washington, D.C: HT Digital Streams Limited
Journal title:US Fed News Service, Including US State News, 2020
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Newsletter articlesFull Text
INTERNATIONAL PATENT: DANA-FARBER CANCER INSTITUTE, INC., CORNELL UNIVERSITY, GRAY, NATHANAEL S., ZHANG, TINGHU, CANTLEY, LEWIS C., SIVAKUMAREN, CARMEN, MANZ, THERESA, WANG, ERIC, JI, WENZHI, FISCHER,...
Publisher:Washington, D.C: HT Digital Streams Limited
Journal title:US Fed News Service, Including US State News, 2022
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ArticlesPeer ReviewedFull Text
Suppression of insulin feedback enhances the efficacy of PI3K inhibitors
Author / Creator:Hopkins, Benjamin D. ; Pauli, Chantal ; Du, Xing ; Wang, Diana G. ; Li, Xiang ; Wu, David ; Amadiume, Solomon C. ; Goncalves, Marcus D. ; Hodakoski, Cindy ; Lundquist, Mark R. ; Bareja, Rohan ; Ma, Yan ; Harris, Emily M. ; Sboner, Andrea ; Beltran, Himisha ; Rubin, Mark A. ; Mukherjee, Siddhartha ; Cantley, Lewis C.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2018-08, Vol.560 (7719), p.499-503
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ArticlesPeer ReviewedFull Text
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
Author / Creator:Vander Heiden, Matthew G ; Cantley, Lewis C ; Thompson, Craig B
Publisher:Washington, DC: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2009-05, Vol.324 (5930), p.1029-1033
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ArticlesPeer ReviewedFull Text
ERK1/2-dependent phosphorylation and nuclear translocation of PKM2 promotes the Warburg effect
Author / Creator:Yang, Weiwei ; Zheng, Yanhua ; Xia, Yan ; Ji, Haitao ; Chen, Xiaomin ; Guo, Fang ; Lyssiotis, Costas A. ; Aldape, Kenneth ; Cantley, Lewis C. ; Lu, Zhimin
Publisher:London: Nature Publishing Group UK
Journal title:Nature cell biology, 2012-12, Vol.14 (12), p.1295-1304
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ArticlesPeer ReviewedFull Text
Identification of SARS-CoV-2 inhibitors using lung and colonic organoids
Author / Creator:Han, Yuling ; Duan, Xiaohua ; Yang, Liuliu ; Nilsson-Payant, Benjamin E. ; Wang, Pengfei ; Duan, Fuyu ; Tang, Xuming ; Yaron, Tomer M. ; Zhang, Tuo ; Uhl, Skyler ; Bram, Yaron ; Richardson, Chanel ; Zhu, Jiajun ; Zhao, Zeping ; Redmond, David ; Houghton, Sean ; Nguyen, Duc-Huy T. ; Xu, Dong ; Wang, Xing ; Jessurun, Jose ; Borczuk, Alain ; Huang, Yaoxing ; Johnson, Jared L. ; Liu, Yuru ; Xiang, Jenny ; Wang, Hui ; Cantley, Lewis C. ; tenOever, Benjamin R. ; Ho, David D. ; Pan, Fong Cheng ; Evans, Todd ; Chen, Huanhuan Joyce ; Schwartz, Robert E. ; Chen, Shuibing
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2021-01, Vol.589 (7841), p.270-275
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ArticlesPeer ReviewedFull Text
The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism
Author / Creator:Engelman, Jeffrey A. ; Luo, Ji ; Cantley, Lewis C.
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Genetics, 2006-08, Vol.7 (8), p.606-619
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ArticlesPeer ReviewedFull Text
Glutathione biosynthesis is a metabolic vulnerability in PI(3)K/Akt-driven breast cancer
Author / Creator:Lien, Evan C. ; Lyssiotis, Costas A. ; Juvekar, Ashish ; Hu, Hai ; Asara, John M. ; Cantley, Lewis C. ; Toker, Alex
Publisher:London: Nature Publishing Group UK
Journal title:Nature cell biology, 2016-05, Vol.18 (5), p.572-578
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ArticlesPeer ReviewedFull Text
The Phosphoinositide 3-Kinase Pathway
Author / Creator:Cantley, Lewis C.
Publisher:United States: American Society for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2002-05, Vol.296 (5573), p.1655-1657
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ArticlesPeer ReviewedFull Text
Inhibition of Pyruvate Kinase M2 by Reactive Oxygen Species Contributes to Cellular Antioxidant Responses
Author / Creator:Anastasiou, Dimitrios ; Poulogiannis, George ; Asara, John M. ; Boxer, Matthew B. ; Jiang, Jian-kang ; Shen, Min ; Bellinger, Gary ; Sasaki, Atsuo T. ; Locasale, Jason W. ; Auld, Douglas S. ; Thomas, Craig J. ; Heiden, Matthew G. Vander ; Cantley, Lewis C.
Publisher:Washington, DC: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2011-12, Vol.334 (6060), p.1278-1283
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ArticlesPeer ReviewedFull Text
Regulation of epithelial tight junction assembly and disassembly by AMP-activated protein kinase
Author / Creator:Zheng, Bin ; Cantley, Lewis C
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2007-01, Vol.104 (3), p.819-822
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ArticlesPeer ReviewedFull Text
Phase II trial of AKT inhibitor MK-2206 in patients with advanced breast cancer who have tumors with PIK3CA or AKT mutations, and/or PTEN loss/PTEN mutation
Author / Creator:Xing, Yan ; Lin, Nancy U ; Maurer, Matthew A ; Chen, Huiqin ; Mahvash, Armeen ; Sahin, Aysegul ; Akcakanat, Argun ; Li, Yisheng ; Abramson, Vandana ; Litton, Jennifer ; Chavez-MacGregor, Mariana ; Valero, Vicente ; Piha-Paul, Sarina A ; Hong, David ; Do, Kim-Anh ; Tarco, Emily ; Riall, Dianna ; Eterovic, Agda Karina ; Wulf, Gerburg M ; Cantley, Lewis C ; Mills, Gordon B ; Doyle, L Austin ; Winer, Eric ; Hortobagyi, Gabriel N ; Gonzalez-Angulo, Ana Maria ; Meric-Bernstam, Funda
Publisher:England: BioMed Central Ltd
Journal title:Breast cancer research : BCR, 2019-07, Vol.21 (1), p.78-78, Article 78
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ArticlesPeer ReviewedFull Text
Phenformin enhances the therapeutic benefit of BRAFⱽ⁶⁰⁰ᴱ inhibition in melanoma
Author / Creator:Yuan, Bing ; Ito, Koichi ; Perez-Lorenzo, Rolando ; Del Guzzo, Christina ; Lee, Jung Hyun ; Shen, Che-Hung ; Bosenberg, Marcus W ; McMahon, Martin ; Cantley, Lewis C ; Zheng, Bin
Publisher:National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2013-11, Vol.110 (45), p.18226-18231
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ArticlesPeer ReviewedFull Text
Identification of a small molecule inhibitor of 3-phosphoglycerate dehydrogenase to target serine biosynthesis in cancers
Author / Creator:Mullarky, Edouard ; Lucki, Natasha C. ; Zavareh, Reza Beheshti ; Anglin, Justin L. ; Gomes, Ana P. ; Nicolay, Brandon N. ; Wong, Jenny C. Y. ; Christen, Stefan ; Takahashi, Hidenori ; Singh, Pradeep K. ; Blenis, John ; Warren, J. David ; Fendt, Sarah-Maria ; Asara, John M. ; DeNicola, Gina M. ; Lyssiotis, Costas A. ; Lairson, Luke L. ; Cantley, Lewis C.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2016-02, Vol.113 (7), p.1778-1783
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ArticlesPeer ReviewedFull Text
Inhibition of mTORC1 leads to MAPK pathway activation through a PI3K-dependent feedback loop in human cancer
Author / Creator:Carracedo, Arkaitz ; Ma, Li ; Teruya-Feldstein, Julie ; Rojo, Federico ; Salmena, Leonardo ; Alimonti, Andrea ; Egia, Ainara ; Sasaki, Atsuo T ; Thomas, George ; Kozma, Sara C ; Papa, Antonella ; Nardella, Caterina ; Cantley, Lewis C ; Baselga, Jose ; Pandolfi, Pier Paolo
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2008-09, Vol.118 (9), p.3065-3074
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ArticlesPeer ReviewedFull Text
Active Pin1 is a key target of all-trans retinoic acid in acute promyelocytic leukemia and breast cancer
Author / Creator:Wei, Shuo ; Kozono, Shingo ; Kats, Lev ; Nechama, Morris ; Li, Wenzong ; Guarnerio, Jlenia ; Luo, Manli ; You, Mi-Hyeon ; Yao, Yandan ; Kondo, Asami ; Hu, Hai ; Bozkurt, Gunes ; Moerke, Nathan J ; Cao, Shugeng ; Reschke, Markus ; Chen, Chun-Hau ; Rego, Eduardo M ; Lo-Coco, Francesco ; Cantley, Lewis C ; Lee, Tae Ho ; Wu, Hao ; Zhang, Yan ; Pandolfi, Pier Paolo ; Zhou, Xiao Zhen ; Lu, Kun Ping
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2015-05, Vol.21 (5), p.457-466
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ArticlesPeer ReviewedFull Text
Biography of Lewis C. Cantley
Author / Creator:Bradley, David
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2004-03, Vol.101 (10), p.3327-3328
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ArticlesPeer ReviewedFull Text
Evidence for an Alternative Glycolytic Pathway in Rapidly Proliferating Cells
Author / Creator:Vander Heiden, Matthew G ; Locasale, Jason W ; Swanson, Kenneth D ; Sharfi, Hadar ; Heffron, Greg J ; Amador-Noguez, Daniel ; Christofk, Heather R ; Wagner, Gerhard ; Rabinowitz, Joshua D ; Asara, John M ; Cantley, Lewis C
Publisher:Washington, DC: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2010-09, Vol.329 (5998), p.1492-1499
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Cancer metabolism: fatty acid oxidation in the limelight

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INTERNATIONAL PATENT: CORNELL UNIVERSITY, THE BRIGHAM AND WOMEN'S HOSPITAL, INC., CANTLEY, LEWIS C., KUCHROO, VIJAY KUMAR, SCHRAMM, MARKUS ALEXANDER, DIXON, KAREN OLIVIA FILES APPLICATION FOR "LOSS OF...

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INTERNATIONAL PATENT: GONCALVES, MARCUS , CANTLEY, LEWIS C. , YUN, JIHYE FILES APPLICATION FOR "ANTI-FRUCTOSE THERAPY FOR COLORECTAL AND SMALL INTESTINE CANCERS"

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INTERNATIONAL PATENT: DANA-FARBER CANCER INSTITUTE, INC., CORNELL UNIVERSITY, GRAY, NATHANAEL S., ZHANG, TINGHU, CANTLEY, LEWIS C., SIVAKUMAREN, CARMEN, MANZ, THERESA, WANG, ERIC, JI, WENZHI, FISCHER,...

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Suppression of insulin feedback enhances the efficacy of PI3K inhibitors

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Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

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ERK1/2-dependent phosphorylation and nuclear translocation of PKM2 promotes the Warburg effect

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Identification of SARS-CoV-2 inhibitors using lung and colonic organoids

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The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism

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Glutathione biosynthesis is a metabolic vulnerability in PI(3)K/Akt-driven breast cancer

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The Phosphoinositide 3-Kinase Pathway

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Inhibition of Pyruvate Kinase M2 by Reactive Oxygen Species Contributes to Cellular Antioxidant Responses

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Regulation of epithelial tight junction assembly and disassembly by AMP-activated protein kinase

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Phase II trial of AKT inhibitor MK-2206 in patients with advanced breast cancer who have tumors with PIK3CA or AKT mutations, and/or PTEN loss/PTEN mutation

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Phenformin enhances the therapeutic benefit of BRAFⱽ⁶⁰⁰ᴱ inhibition in melanoma

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Identification of a small molecule inhibitor of 3-phosphoglycerate dehydrogenase to target serine biosynthesis in cancers

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Inhibition of mTORC1 leads to MAPK pathway activation through a PI3K-dependent feedback loop in human cancer

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Active Pin1 is a key target of all-trans retinoic acid in acute promyelocytic leukemia and breast cancer

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Biography of Lewis C. Cantley

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Evidence for an Alternative Glycolytic Pathway in Rapidly Proliferating Cells

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