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Lineage-specific and single-cell chromatin accessibility charts human hematopoiesis and leukemia evo...

Lineage-specific and single-cell chromatin accessibility charts human hematopoiesis and leukemia evo...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5042844

Lineage-specific and single-cell chromatin accessibility charts human hematopoiesis and leukemia evolution

About this item

Full title

Lineage-specific and single-cell chromatin accessibility charts human hematopoiesis and leukemia evolution

Publisher

New York: Nature Publishing Group US

Journal title

Nature genetics, 2016-10, Vol.48 (10), p.1193-1203

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Howard Chang, Ravindra Majeti and colleagues define the chromatin accessibility and transcriptional landscapes in 13 human primary blood cell types and in acute myeloid leukemia cells. They identify potential regulators governing hematopoietic differentiation and genetic elements linked to regulatory evolution in cancer cells.
We define the chro...

Alternative Titles

Full title

Lineage-specific and single-cell chromatin accessibility charts human hematopoiesis and leukemia evolution

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5042844

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5042844

Other Identifiers

ISSN

1061-4036,1546-1718

E-ISSN

1546-1718

DOI

10.1038/ng.3646

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