Replenishment of microRNA-188-5p restores the synaptic and cognitive deficits in 5XFAD Mouse Model o...
Replenishment of microRNA-188-5p restores the synaptic and cognitive deficits in 5XFAD Mouse Model of Alzheimer’s Disease
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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MicroRNAs have emerged as key factors in development, neurogenesis and synaptic functions in the central nervous system. In the present study, we investigated a pathophysiological significance of microRNA-188-5p (miR-188-5p) in Alzheimer’s disease (AD). We found that oligomeric Aβ
1-42
treatment diminished miR-188-5p expression in primary hip...
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Replenishment of microRNA-188-5p restores the synaptic and cognitive deficits in 5XFAD Mouse Model of Alzheimer’s Disease
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5052619
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5052619
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2045-2322
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2045-2322
DOI
10.1038/srep34433