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Deletion of the mu opioid receptor gene in mice reshapes the reward–aversion connectome

Deletion of the mu opioid receptor gene in mice reshapes the reward–aversion connectome

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5068324

Deletion of the mu opioid receptor gene in mice reshapes the reward–aversion connectome

About this item

Full title

Deletion of the mu opioid receptor gene in mice reshapes the reward–aversion connectome

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2016-10, Vol.113 (41), p.11603-11608

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Connectome genetics seeks to uncover how genetic factors shape brain functional connectivity; however, the causal impact of a single gene’s activity on whole-brain networks remains unknown. We tested whether the sole targeted deletion of the mu opioid receptor gene (Oprm1) alters the brain connectome in living mice. Hypothesis-free analysis of comb...

Alternative Titles

Full title

Deletion of the mu opioid receptor gene in mice reshapes the reward–aversion connectome

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5068324

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5068324

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1601640113

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