MAVS-dependent host species range and pathogenicity of human hepatitis A virus
MAVS-dependent host species range and pathogenicity of human hepatitis A virus
About this item
Full title
Author / Creator
Hirai-Yuki, Asuka , Hensley, Lucinda , McGivern, David R. , González-López, Olga , Das, Anshuman , Feng, Hui , Sun, Lu , Wilson, Justin E. , Hu, Fengyu , Feng, Zongdi , Lovell, William , Misumi, Ichiro , Ting, Jenny P.-Y. , Montgomery, Stephanie , Cullen, John , Whitmire, Jason K. and Lemon, Stanley M.
Publisher
United States: American Association for the Advancement of Science
Journal title
Language
English
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Publication information
Publisher
United States: American Association for the Advancement of Science
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More information
Scope and Contents
Contents
Hepatotropic viruses are important causes of human disease, but the intrahepatic immune response to hepatitis viruses is poorly understood because of a lack of tractable smallanimal models. We describe a murine model of hepatitis A virus (HAV) infection that recapitulates critical features of type A hepatitis in humans. We demonstrate that the capa...
Alternative Titles
Full title
MAVS-dependent host species range and pathogenicity of human hepatitis A virus
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5068972
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5068972
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.aaf8325
