Exploiting the neoantigen landscape for immunotherapy of pancreatic ductal adenocarcinoma
Exploiting the neoantigen landscape for immunotherapy of pancreatic ductal adenocarcinoma
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Immunotherapy approaches for pancreatic ductal adenocarcinoma (PDAC) have met with limited success. It has been postulated that a low mutation load may lead to a paucity of T cells within the tumor microenvironment (TME). However, it is also possible that while neoantigens are present, an effective immune response cannot be generated due to an immu...
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Full title
Exploiting the neoantigen landscape for immunotherapy of pancreatic ductal adenocarcinoma
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5071896
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5071896
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep35848