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Exploiting the neoantigen landscape for immunotherapy of pancreatic ductal adenocarcinoma

Exploiting the neoantigen landscape for immunotherapy of pancreatic ductal adenocarcinoma

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5071896

Exploiting the neoantigen landscape for immunotherapy of pancreatic ductal adenocarcinoma

About this item

Full title

Exploiting the neoantigen landscape for immunotherapy of pancreatic ductal adenocarcinoma

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2016-10, Vol.6 (1), p.35848-35848, Article 35848

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Immunotherapy approaches for pancreatic ductal adenocarcinoma (PDAC) have met with limited success. It has been postulated that a low mutation load may lead to a paucity of T cells within the tumor microenvironment (TME). However, it is also possible that while neoantigens are present, an effective immune response cannot be generated due to an immu...

Alternative Titles

Full title

Exploiting the neoantigen landscape for immunotherapy of pancreatic ductal adenocarcinoma

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5071896

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5071896

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/srep35848

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