Apoptosis of Sertoli cells after conditional ablation of murine double minute 2 (Mdm2) gene is p53-d...
Apoptosis of Sertoli cells after conditional ablation of murine double minute 2 (Mdm2) gene is p53-dependent and results in male sterility
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Author / Creator
Fouchécourt, S , Livera, G , Messiaen, S , Fumel, B , Parent, A-S , Marine, J-C and Monget, P
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Beside its well-documented role in carcinogenesis, the function of p53 family has been more recently revealed in development and female reproduction, but it is still poorly documented in male reproduction. We specifically tested this possibility by ablating Mdm2, an E3 ligase that regulates p53 protein stability and transactivation function, specif...
Alternative Titles
Full title
Apoptosis of Sertoli cells after conditional ablation of murine double minute 2 (Mdm2) gene is p53-dependent and results in male sterility
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5072445
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5072445
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ISSN
1350-9047,1476-5403
E-ISSN
1476-5403
DOI
10.1038/cdd.2015.120
