Estimating the population abundance of tissue-infiltrating immune and stromal cell populations using...
Estimating the population abundance of tissue-infiltrating immune and stromal cell populations using gene expression
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
We introduce the Microenvironment Cell Populations-counter (MCP-counter) method, which allows the robust quantification of the absolute abundance of eight immune and two stromal cell populations in heterogeneous tissues from transcriptomic data. We present in vitro mRNA mixture and ex vivo immunohistochemical data that quantitatively support the va...
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Full title
Estimating the population abundance of tissue-infiltrating immune and stromal cell populations using gene expression
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5073889
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5073889
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ISSN
1474-760X,1474-7596,1465-6906
E-ISSN
1474-760X
DOI
10.1186/s13059-016-1070-5