IL-15 functions as a danger signal to regulate tissue-resident T cells and tissue destruction
IL-15 functions as a danger signal to regulate tissue-resident T cells and tissue destruction
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Contents
This Opinion article proposes that interleukin-15 (IL-15) is a master regulator of tissue-specific T cell responses to promote the destruction of infected cells. Hence, dysregulation of IL-15 production in tissues during sterile inflammation can lead to T cell-mediated autoimmunity.
In this Opinion article, we discuss the function of tissues as...
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Full title
IL-15 functions as a danger signal to regulate tissue-resident T cells and tissue destruction
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5079184
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5079184
Other Identifiers
ISSN
1474-1733
E-ISSN
1474-1741
DOI
10.1038/nri3919
