Palladium-catalysed transannular C–H functionalization of alicyclic amines
Palladium-catalysed transannular C–H functionalization of alicyclic amines
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Contents
An approach to selectively manipulate the C–H bonds of alicyclic amines at sites remote to nitrogen is demonstrated by the synthesis of new derivatives of several bioactive molecules, including varenicline, a drug used to treat nicotine addiction.
A new route to bioactive piperidine derivatives
Saturated nitrogen-containing heterocycles are f...
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Full title
Palladium-catalysed transannular C–H functionalization of alicyclic amines
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5082708
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5082708
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature16957