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Interleukin-22 ameliorates liver fibrosis through miR-200a/beta-catenin

Interleukin-22 ameliorates liver fibrosis through miR-200a/beta-catenin

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5098253

Interleukin-22 ameliorates liver fibrosis through miR-200a/beta-catenin

About this item

Full title

Interleukin-22 ameliorates liver fibrosis through miR-200a/beta-catenin

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2016-11, Vol.6 (1), p.36436, Article 36436

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

IL-22 ameliorates liver fibrosis by inhibiting hepatic stellate cells (HSC), and loss of miR-200a is associated with the development of liver fibrosis. The study aimed to investigate the interplay between IL-22 and miR-200a in regulating liver fibrosis
in vivo
and
in vitro
. We observed that IL-22 significantly reduced the proliferation...

Alternative Titles

Full title

Interleukin-22 ameliorates liver fibrosis through miR-200a/beta-catenin

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5098253

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5098253

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/srep36436

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