Oxidative stress in oocytes during midprophase induces premature loss of cohesion and chromosome seg...
Oxidative stress in oocytes during midprophase induces premature loss of cohesion and chromosome segregation errors
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Publisher
United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Contents
In humans, errors in meiotic chromosome segregation that produce aneuploid gametes increase dramatically as women age, a phenomenon termed the “maternal age effect.” During meiosis, cohesion between sister chromatids keeps recombinant homologs physically attached and premature loss of cohesion can lead to missegregation of homologs during meiosis I...
Alternative Titles
Full title
Oxidative stress in oocytes during midprophase induces premature loss of cohesion and chromosome segregation errors
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5098651
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5098651
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1612047113
