Slowing ageing by design: the rise of NAD+ and sirtuin-activating compounds
Slowing ageing by design: the rise of NAD+ and sirtuin-activating compounds
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Key Points
Sirtuins are a critical component of evolutionarily conserved longevity pathways. Sirtuins are nicotinamide adenine dinucleotide (NAD
+
)-dependent lysine deacylases that promote longevity and healthy ageing.
Sirtuin-activating compounds (STACs) bind to and allosterically modulate the affinity of SIRT1 for NAD
+
and pro...
Alternative Titles
Full title
Slowing ageing by design: the rise of NAD+ and sirtuin-activating compounds
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5107309
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5107309
Other Identifiers
ISSN
1471-0072
E-ISSN
1471-0080
DOI
10.1038/nrm.2016.93
