Calpain-mediated cleavage of collapsin response mediator protein-2 drives acute axonal degeneration
Calpain-mediated cleavage of collapsin response mediator protein-2 drives acute axonal degeneration
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Axonal degeneration is a key initiating event in many neurological diseases. Focal lesions to axons result in a rapid disintegration of the perilesional axon by acute axonal degeneration (AAD) within several hours. However, the underlying molecular mechanisms of AAD are only incompletely understood. Here, we studied AAD
in vivo
through live-i...
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Full title
Calpain-mediated cleavage of collapsin response mediator protein-2 drives acute axonal degeneration
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5109185
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5109185
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep37050
