Log in to save to my catalogue

Selective integrin endocytosis is driven by interactions between the integrin α-chain and AP2

Selective integrin endocytosis is driven by interactions between the integrin α-chain and AP2

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5130146

Selective integrin endocytosis is driven by interactions between the integrin α-chain and AP2

About this item

Full title

Selective integrin endocytosis is driven by interactions between the integrin α-chain and AP2

Publisher

New York: Nature Publishing Group US

Journal title

Nature structural & molecular biology, 2016-02, Vol.23 (2), p.172-179

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

An evolutionarily conserved YxxΦ motif present in a subset of integrin α-chains directs selective endocytosis of integrin heterodimers via interaction with the clathrin adaptor AP2, which is important for cell motility.
Integrins are heterodimeric cell-surface adhesion molecules comprising one of 18 possible α-chains and one of eight possible β-...

Alternative Titles

Full title

Selective integrin endocytosis is driven by interactions between the integrin α-chain and AP2

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5130146

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5130146

Other Identifiers

ISSN

1545-9993

E-ISSN

1545-9985

DOI

10.1038/nsmb.3161

How to access this item