Stromal cells control the epithelial residence of DCs and memory T cells by regulated activation of...
Stromal cells control the epithelial residence of DCs and memory T cells by regulated activation of TGF-β
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Author / Creator
Mohammed, Javed , Beura, Lalit K , Bobr, Aleh , Astry, Brian , Chicoine, Brian , Kashem, Sakeen W , Welty, Nathan E , Igyártó, Botond Z , Wijeyesinghe, Sathi , Thompson, Emily A , Matte, Catherine , Bartholin, Laurent , Kaplan, Alesia , Sheppard, Dean , Bridges, Alina G , Shlomchik, Warren D , Masopust, David and Kaplan, Daniel H
Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Scope and Contents
Contents
The cytokine TGF-β maintains the residency of cells of the immune system in barrier tissues. Kaplan and colleagues demonstrate that specific integrins expressed by epithelial cells activate latent TGF-β and that this is critical to maintain residency of cells of the immune system in the skin and gut.
Cells of the immune system that reside in bar...
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Full title
Stromal cells control the epithelial residence of DCs and memory T cells by regulated activation of TGF-β
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5135085
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5135085
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ISSN
1529-2908,1529-2916
E-ISSN
1529-2916
DOI
10.1038/ni.3396