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Activation of NMDA receptors and the mechanism of inhibition by ifenprodil

Activation of NMDA receptors and the mechanism of inhibition by ifenprodil

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5136294

Activation of NMDA receptors and the mechanism of inhibition by ifenprodil

About this item

Full title

Activation of NMDA receptors and the mechanism of inhibition by ifenprodil

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2016-06, Vol.534 (7605), p.63-68

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The physiology of
N
-methyl-
d
-aspartate (NMDA) receptors is fundamental to brain development and function. NMDA receptors are ionotropic glutamate receptors that function as heterotetramers composed mainly of GluN1 and GluN2 subunits. Activation of NMDA receptors requires binding of neurotransmitter agonists to a ligand-binding domain...

Alternative Titles

Full title

Activation of NMDA receptors and the mechanism of inhibition by ifenprodil

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5136294

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5136294

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/nature17679

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