ProteoPlex: stability optimization of macromolecular complexes by sparse-matrix screening of chemica...
ProteoPlex: stability optimization of macromolecular complexes by sparse-matrix screening of chemical space
About this item
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Author / Creator
Chari, Ashwin , Haselbach, David , Kirves, Jan-Martin , Ohmer, Juergen , Paknia, Elham , Fischer, Niels , Ganichkin, Oleg , Möller, Vanessa , Frye, Jeremiah J , Petzold, Georg , Jarvis, Marc , Tietzel, Michael , Grimm, Clemens , Peters, Jan-Michael , Schulman, Brenda A , Tittmann, Kai , Markl, Jürgen , Fischer, Utz and Stark, Holger
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publication information
Publisher
New York: Nature Publishing Group US
Subjects
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Scope and Contents
Contents
ProteoPlex optimizes buffer conditions for the isolation and purification of macromolecular complexes. The concurrent complex stabilization is beneficial for structure determination using X-ray crystallography or cryo-electron microscopy.
Molecular machines or macromolecular complexes are supramolecular assemblies of biomolecules with a variety...
Alternative Titles
Full title
ProteoPlex: stability optimization of macromolecular complexes by sparse-matrix screening of chemical space
Authors, Artists and Contributors
Author / Creator
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5136620
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5136620
Other Identifiers
ISSN
1548-7091
E-ISSN
1548-7105
DOI
10.1038/nmeth.3493
