Identification of an anti-inflammatory protein from Faecalibacterium prausnitzii, a commensal bacter...
Identification of an anti-inflammatory protein from Faecalibacterium prausnitzii, a commensal bacterium deficient in Crohn’s disease
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Author / Creator
Quévrain, E , Maubert, M A , Michon, C , Chain, F , Marquant, R , Tailhades, J , Miquel, S , Carlier, L , Bermúdez-Humarán, L G , Pigneur, B , Lequin, O , Kharrat, P , Thomas, G , Rainteau, D , Aubry, C , Breyner, N , Afonso, C , Lavielle, S , Grill, J-P , Chassaing, G , Chatel, J M , Trugnan, G , Xavier, R , Langella, P , Sokol, H and Seksik, P
Publisher
England: BMJ Publishing Group LTD
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Language
English
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Publisher
England: BMJ Publishing Group LTD
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Contents
BackgroundCrohn’s disease (CD)-associated dysbiosis is characterised by a loss of Faecalibacterium prausnitzii, whose culture supernatant exerts an anti-inflammatory effect both in vitro and in vivo. However, the chemical nature of the anti-inflammatory compounds has not yet been determined.MethodsPeptidomic analysis using mass spectrometry was app...
Alternative Titles
Full title
Identification of an anti-inflammatory protein from Faecalibacterium prausnitzii, a commensal bacterium deficient in Crohn’s disease
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5136800
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5136800
Other Identifiers
ISSN
0017-5749
E-ISSN
1468-3288
DOI
10.1136/gutjnl-2014-307649
