Structure and dynamics of a constitutively active neurotensin receptor
Structure and dynamics of a constitutively active neurotensin receptor
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Many G protein-coupled receptors show constitutive activity, resulting in the production of a second messenger in the absence of an agonist; and naturally occurring constitutively active mutations in receptors have been implicated in diseases. To gain insight into mechanistic aspects of constitutive activity, we report here the 3.3 Å crystal struct...
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Full title
Structure and dynamics of a constitutively active neurotensin receptor
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5141500
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5141500
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep38564
