Inhibition of mTOR induces a paused pluripotent state
Inhibition of mTOR induces a paused pluripotent state
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Inhibition of mechanistic target of rapamycin (mTOR) suspends mouse blastocyst development and the cells remain ‘paused’ in a reversible pluripotent state, allowing prolonged culture.
mTOR inhibition prompts novel pluripotent state
Although pluripotent stem cells can be propagated indefinitely
in vitro
, pluripotency is usually a transi...
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Full title
Inhibition of mTOR induces a paused pluripotent state
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5143278
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5143278
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature20578
