FGFR1 and NTRK3 actionable alterations in “Wild-Type” gastrointestinal stromal tumors
FGFR1 and NTRK3 actionable alterations in “Wild-Type” gastrointestinal stromal tumors
About this item
Full title
Author / Creator
Shi, Eileen , Chmielecki, Juliann , Tang, Chih-Min , Wang, Kai , Heinrich, Michael C. , Kang, Guhyun , Corless, Christopher L. , Hong, David , Fero, Katherine E. , Murphy, James D. , Fanta, Paul T. , Ali, Siraj M. , De Siena, Martina , Burgoyne, Adam M. , Movva, Sujana , Madlensky, Lisa , Heestand, Gregory M. , Trent, Jonathan C. , Kurzrock, Razelle , Morosini, Deborah , Ross, Jeffrey S. , Harismendy, Olivier and Sicklick, Jason K.
Publisher
England: BioMed Central Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: BioMed Central Ltd
Subjects
More information
Scope and Contents
Contents
About 10-15% of adult, and most pediatric, gastrointestinal stromal tumors (GIST) lack mutations in KIT, PDGFRA, SDHx, or RAS pathway components (KRAS, BRAF, NF1). The identification of additional mutated genes in this rare subset of tumors can have important clinical benefit to identify altered biological pathways and select targeted therapies.
Alternative Titles
Full title
FGFR1 and NTRK3 actionable alterations in “Wild-Type” gastrointestinal stromal tumors
Authors, Artists and Contributors
Author / Creator
Chmielecki, Juliann
Tang, Chih-Min
Wang, Kai
Heinrich, Michael C.
Kang, Guhyun
Corless, Christopher L.
Hong, David
Fero, Katherine E.
Murphy, James D.
Fanta, Paul T.
Ali, Siraj M.
De Siena, Martina
Burgoyne, Adam M.
Movva, Sujana
Madlensky, Lisa
Heestand, Gregory M.
Trent, Jonathan C.
Kurzrock, Razelle
Morosini, Deborah
Ross, Jeffrey S.
Harismendy, Olivier
Sicklick, Jason K.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5157084
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5157084
Other Identifiers
ISSN
1479-5876
E-ISSN
1479-5876
DOI
10.1186/s12967-016-1075-6
