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Regulation of breathing by CO2 requires the proton-activated receptor GPR4 in retrotrapezoid nucleus...

Regulation of breathing by CO2 requires the proton-activated receptor GPR4 in retrotrapezoid nucleus...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5171229

Regulation of breathing by CO2 requires the proton-activated receptor GPR4 in retrotrapezoid nucleus neurons

About this item

Full title

Regulation of breathing by CO2 requires the proton-activated receptor GPR4 in retrotrapezoid nucleus neurons

Publisher

Washington: The American Association for the Advancement of Science

Journal title

Science (American Association for the Advancement of Science), 2015-06, Vol.348 (6240), p.1255-1260

Language

English

Formats

Publication information

Publisher

Washington: The American Association for the Advancement of Science

More information

Scope and Contents

Contents

Receptor in the brain controls breathingControl of breathing in mammals depends primarily not on sensing oxygen, but rather on detecting concentrations of carbon dioxide in the blood. Failure of this system can cause potentially deadly sleep apnias. Taking a hint from insects, which use a heterotrimeric guanine nucleotide-binding protein-coupled re...

Alternative Titles

Full title

Regulation of breathing by CO2 requires the proton-activated receptor GPR4 in retrotrapezoid nucleus neurons

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5171229

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5171229

Other Identifiers

ISSN

0036-8075

E-ISSN

1095-9203

DOI

10.1126/science.aaa0922

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