Driver gene classification reveals a substantial overrepresentation of tumor suppressors among very...
Driver gene classification reveals a substantial overrepresentation of tumor suppressors among very large chromatin-regulating proteins
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Compiling a comprehensive list of cancer driver genes is imperative for oncology diagnostics and drug development. While driver genes are typically discovered by analysis of tumor genomes, infrequently mutated driver genes often evade detection due to limited sample sizes. Here, we address sample size limitations by integrating tumor genomics data...
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Full title
Driver gene classification reveals a substantial overrepresentation of tumor suppressors among very large chromatin-regulating proteins
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5180091
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5180091
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep38988
