MT5-MMP Promotes Alzheimer's Pathogenesis in the Frontal Cortex of 5xFAD Mice and APP Trafficking in...
MT5-MMP Promotes Alzheimer's Pathogenesis in the Frontal Cortex of 5xFAD Mice and APP Trafficking in vitro
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Author / Creator
Baranger, Kévin , Bonnet, Amandine E , Girard, Stéphane D , Paumier, Jean-Michel , García-González, Laura , Elmanaa, Wejdane , Bernard, Anne , Charrat, Eliane , Stephan, Delphine , Bauer, Charlotte , Moschke, Katrin , Lichtenthaler, Stefan F , Roman, François S , Checler, Frédéric , Khrestchatisky, Michel and Rivera, Santiago
Publisher
Switzerland: Frontiers Research Foundation
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English
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Publisher
Switzerland: Frontiers Research Foundation
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Contents
We previously reported that deficiency of membrane-type five matrix metalloproteinase (MT5-MMP) prevents amyloid pathology in the cortex and hippocampus of 5xFAD mice, and ameliorates the functional outcome. We have now investigated whether the integrity of another important area affected in Alzheimer's disease (AD), the frontal cortex, was also pr...
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MT5-MMP Promotes Alzheimer's Pathogenesis in the Frontal Cortex of 5xFAD Mice and APP Trafficking in vitro
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5223243
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5223243
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ISSN
1662-5099
E-ISSN
1662-5099
DOI
10.3389/fnmol.2016.00163
