Overexpression of PBK/TOPK relates to tumour malignant potential and poor outcome of gastric carcino...
Overexpression of PBK/TOPK relates to tumour malignant potential and poor outcome of gastric carcinoma
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Background:
PDZ-binding kinase/T-LAK cell-originated protein kinase (PBK/TOPK) is a serine–threonine kinase and overexpressed in various types of cancer by inhibiting the transactivation activities of p53 and PTEN. We tested whether PBK/TOPK acts as a cancer-promoting gene through its activation/overexpression in gastric cancer (GC).
Methods:...
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Full title
Overexpression of PBK/TOPK relates to tumour malignant potential and poor outcome of gastric carcinoma
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5243986
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5243986
Other Identifiers
ISSN
0007-0920
E-ISSN
1532-1827
DOI
10.1038/bjc.2016.394
