A conserved TLR5 binding and activation hot spot on flagellin
A conserved TLR5 binding and activation hot spot on flagellin
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Flagellin is a bacterial protein that polymerizes into the flagellar filament and is essential for bacterial motility. When flagellated bacteria invade the host, flagellin is recognized by Toll-like receptor 5 (TLR5) as a pathogen invasion signal and eventually evokes the innate immune response. Here, we provide a conserved structural mechanism by...
Alternative Titles
Full title
A conserved TLR5 binding and activation hot spot on flagellin
Authors, Artists and Contributors
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5247705
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5247705
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep40878
