Locus coeruleus cellular and molecular pathology during the progression of Alzheimer's disease
Locus coeruleus cellular and molecular pathology during the progression of Alzheimer's disease
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
A major feature of Alzheimer's disease (AD) is the loss of noradrenergic locus coeruleus (LC) projection neurons that mediate attention, memory, and arousal. However, the extent to which the LC projection system degenerates during the initial stages of AD is still under investigation. To address this question, we performed tyrosine hydroxylase (TH)...
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Full title
Locus coeruleus cellular and molecular pathology during the progression of Alzheimer's disease
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5251221
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5251221
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ISSN
2051-5960
E-ISSN
2051-5960
DOI
10.1186/s40478-017-0411-2