TM7SF3, a novel p53-regulated homeostatic factor, attenuates cellular stress and the subsequent indu...
TM7SF3, a novel p53-regulated homeostatic factor, attenuates cellular stress and the subsequent induction of the unfolded protein response
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Publisher
London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Earlier reported small interfering RNA (siRNA) high-throughput screens, identified seven-transmembrane superfamily member 3 (TM7SF3) as a novel inhibitor of pancreatic
β
-cell death. Here we show that TM7SF3 maintains protein homeostasis and promotes cell survival through attenuation of ER stress. Overexpression of TM7SF3 inhibits caspase 3/7...
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TM7SF3, a novel p53-regulated homeostatic factor, attenuates cellular stress and the subsequent induction of the unfolded protein response
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5260493
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5260493
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ISSN
1350-9047
E-ISSN
1476-5403
DOI
10.1038/cdd.2016.108
