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MerTK receptor cleavage promotes plaque necrosis and defective resolution in atherosclerosis

MerTK receptor cleavage promotes plaque necrosis and defective resolution in atherosclerosis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5272169

MerTK receptor cleavage promotes plaque necrosis and defective resolution in atherosclerosis

About this item

Full title

MerTK receptor cleavage promotes plaque necrosis and defective resolution in atherosclerosis

Publisher

United States: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2017-02, Vol.127 (2), p.564-568

Language

English

Formats

Publication information

Publisher

United States: American Society for Clinical Investigation

More information

Scope and Contents

Contents

Atherothrombotic vascular disease is often triggered by a distinct type of atherosclerotic lesion that displays features of impaired inflammation resolution, notably a necrotic core and thinning of a protective fibrous cap that overlies the core. A key cause of plaque necrosis is defective clearance of apoptotic cells, or efferocytosis, by lesional...

Alternative Titles

Full title

MerTK receptor cleavage promotes plaque necrosis and defective resolution in atherosclerosis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5272169

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5272169

Other Identifiers

ISSN

0021-9738

E-ISSN

1558-8238

DOI

10.1172/JCI90520

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