CD34⁺ mesenchymal cells are a major component of the intestinal stem cells niche at homeostasis and...
CD34⁺ mesenchymal cells are a major component of the intestinal stem cells niche at homeostasis and after injury
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United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
The intestinal epithelium is continuously renewed by intestinal epithelial stem cells (IESCs) positioned at the base of each crypt. Mesenchymal-derived factors are essential to maintain IESCs; however, the cellular composition and development of such mesenchymal niche remains unclear. Here, we identify pericryptal CD34⁺ Gp38⁺ αSMA⁻ mesenchymal cell...
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Full title
CD34⁺ mesenchymal cells are a major component of the intestinal stem cells niche at homeostasis and after injury
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5278455
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5278455
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1620059114