Two strategies to engineer flexible loops for improved enzyme thermostability
Two strategies to engineer flexible loops for improved enzyme thermostability
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Flexible sites are potential targets for engineering the stability of enzymes. Nevertheless, the success rate of the rigidifying flexible sites (RFS) strategy is still low due to a limited understanding of how to determine the best mutation candidates. In this study, two parallel strategies were applied to identify mutation candidates within the fl...
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Full title
Two strategies to engineer flexible loops for improved enzyme thermostability
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5286519
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5286519
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep41212
