Structure and activation of C1, the complex initiating the classical pathway of the complement casca...
Structure and activation of C1, the complex initiating the classical pathway of the complement cascade
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Publisher
United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Contents
The complement system is an important antimicrobial and inflammation-generating component of the innate immune system. The classical pathway of complement is activated upon binding of the 774-kDa C1 complex, consisting of the recognitionmolecule C1q and the tetrameric protease complex C1r₂s₂, to a variety of activators presenting specific molecular...
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Full title
Structure and activation of C1, the complex initiating the classical pathway of the complement cascade
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5293073
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5293073
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1616998114
