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Blockade to pathological remodeling of infarcted heart tissue using a porcupine antagonist

Blockade to pathological remodeling of infarcted heart tissue using a porcupine antagonist

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5320972

Blockade to pathological remodeling of infarcted heart tissue using a porcupine antagonist

About this item

Full title

Blockade to pathological remodeling of infarcted heart tissue using a porcupine antagonist

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2017-02, Vol.114 (7), p.1649-1654

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

The secreted Wnt signaling molecules are essential to the coordination of cell-fate decision making in multicellular organisms. In adult animals, the secreted Wnt proteins are critical for tissue regeneration and frequently contribute to cancer. Small molecules that disable the Wnt acyltransferase Porcupine (Porcn) are candidate anticancer agents i...

Alternative Titles

Full title

Blockade to pathological remodeling of infarcted heart tissue using a porcupine antagonist

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5320972

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5320972

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1621346114

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