Yes-associated protein mediates immune reprogramming in pancreatic ductal adenocarcinoma
Yes-associated protein mediates immune reprogramming in pancreatic ductal adenocarcinoma
About this item
Full title
Author / Creator
Murakami, S , Shahbazian, D , Surana, R , Zhang, W , Chen, H , Graham, G T , White, S M , Weiner, L M and Yi, C
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Pancreatic ductal adenocarcinoma (PDAC) is characterized by a high degree of inflammation and profound immune suppression. Here we identify Yes-associated protein (Yap) as a critical regulator of the immunosuppressive microenvironment in both mouse and human PDAC. Within
Kras:p53
mutant pancreatic ductal cells, Yap drives the expression and s...
Alternative Titles
Full title
Yes-associated protein mediates immune reprogramming in pancreatic ductal adenocarcinoma
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5322249
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5322249
Other Identifiers
ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/onc.2016.288
