Integrated Organotypic Slice Cultures and RT-QuIC (OSCAR) Assay: Implications for Translational Disc...
Integrated Organotypic Slice Cultures and RT-QuIC (OSCAR) Assay: Implications for Translational Discovery in Protein Misfolding Diseases
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Contents
Protein misfolding is a key pathological event in neurodegenerative diseases like prion diseases, synucleinopathies, and tauopathies that are collectively termed protein misfolding disorders. Prions are a prototypic model to study protein aggregation biology and therapeutic development. Attempts to develop anti-prion therapeutics have been impeded...
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Integrated Organotypic Slice Cultures and RT-QuIC (OSCAR) Assay: Implications for Translational Discovery in Protein Misfolding Diseases
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5324099
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5324099
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep43155
