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Unsupervised detection of cancer driver mutations with parsimony-guided learning

Unsupervised detection of cancer driver mutations with parsimony-guided learning

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5328615

Unsupervised detection of cancer driver mutations with parsimony-guided learning

About this item

Full title

Unsupervised detection of cancer driver mutations with parsimony-guided learning

Publisher

New York: Nature Publishing Group US

Journal title

Nature genetics, 2016-10, Vol.48 (10), p.1288-1294

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Runjun Kumar, S. Joshua Swamidass and Ron Bose present an unsupervised parsimony-guided method, ParsSNP, for prioritizing candidate cancer driver mutations. They apply ParsSNP to a gastric cancer data set and predict potential driver mutations not detected by other methods, including truncations in known tumor-suppressor genes and previously confir...

Alternative Titles

Full title

Unsupervised detection of cancer driver mutations with parsimony-guided learning

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5328615

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5328615

Other Identifiers

ISSN

1061-4036

E-ISSN

1546-1718

DOI

10.1038/ng.3658

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