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GSK-3 is a master regulator of neural progenitor homeostasis

GSK-3 is a master regulator of neural progenitor homeostasis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5328673

GSK-3 is a master regulator of neural progenitor homeostasis

About this item

Full title

GSK-3 is a master regulator of neural progenitor homeostasis

Publisher

New York: Nature Publishing Group US

Journal title

Nature neuroscience, 2009-11, Vol.12 (11), p.1390-1397

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

The authors report the conditional deletion of the alpha and beta forms of glycogen synthase kinase 3 (GSK-3) in mouse neural progenitors. This deletion is associated with dysregulations in β-catenin, Sonic Hedgehog, Notch and fibroblast growth factor signaling pathways and leads to markedly increased proliferation of neural progenitors.
The dev...

Alternative Titles

Full title

GSK-3 is a master regulator of neural progenitor homeostasis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5328673

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5328673

Other Identifiers

ISSN

1097-6256

E-ISSN

1546-1726

DOI

10.1038/nn.2408

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