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Cholesterol impairment contributes to neuroserpin aggregation

Cholesterol impairment contributes to neuroserpin aggregation

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5334643

Cholesterol impairment contributes to neuroserpin aggregation

About this item

Full title

Cholesterol impairment contributes to neuroserpin aggregation

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2017-03, Vol.7 (1), p.43669-43669, Article 43669

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Intraneural accumulation of misfolded proteins is a common feature of several neurodegenerative pathologies including Alzheimer’s and Parkinson’s diseases, and Familial Encephalopathy with Neuroserpin Inclusion Bodies (FENIB). FENIB is a rare disease due to a point mutation in neuroserpin which accelerates protein aggregation in the endoplasmic ret...

Alternative Titles

Full title

Cholesterol impairment contributes to neuroserpin aggregation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5334643

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5334643

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/srep43669

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