Astrocyte pathology in a human neural stem cell model of frontotemporal dementia caused by mutant TA...
Astrocyte pathology in a human neural stem cell model of frontotemporal dementia caused by mutant TAU protein
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Astroglial pathology is seen in various neurodegenerative diseases including frontotemporal dementia (FTD), which can be caused by mutations in the gene encoding the microtubule-associated protein TAU (
MAPT
). Here, we applied a stem cell model of FTD to examine if FTD astrocytes carry an intrinsic propensity to degeneration and to determine...
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Full title
Astrocyte pathology in a human neural stem cell model of frontotemporal dementia caused by mutant TAU protein
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5335603
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5335603
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep42991
